Infant with Life Threatening Thymic Carcinoma

Basil Kadhim Abdullah; Zardasht Bakr Mohammed; Khalid Hama Salih; Aram Baram; Dashti Latif Muhealddina; Ali Omer Qadir; Rebwar Ahmed Shrif; Rzgar Ghareeb Muhamed

doi:10.21467/ias.7.1.53-57

Authors

Basil Kadhim Abdullah Pediatric Department-Hiwa Teaching Hospital, Sulemania
Zardasht Bakr Mohammed Pediatric Department, Hiwa Teaching Hospital, Sulemania
Khalid Hama Salih Pediatrics Department, College of Medicine, University of Sulaimania
Aram Baram Department of Cardiovascular and Thoracic Surgery, School of Medicine, University of Sulaimania
Dashti Latif Muhealddina Hiwa Teaching Hospital, Sulemania
Ali Omer Qadir Pediatric Department, Hiwa Teaching Hospital, Sulemania
Rebwar Ahmed Shrif Pediatric Department, Hiwa Teaching Hospital, Sulemania
Rzgar Ghareeb Muhamed Department of Cardiovascular and Thoracic Surgery, School of Medicine, University of Sulaimania

DOI:

https://doi.org/10.21467/ias.7.1.53-57

Abstract

Thymic epithelial neoplasms consist of thymomas, thymic carcinoids and thymic carcinomas. Carcinomas are malignant tumors of the thymus; they compromise only 4%-14% of thymic epithelial neoplasms. Thymic carcinoma cells do not resemble healthy cells but similar to cancer cells that originate from other parts of the body and grow more quickly when the tumor is found and more difficult to treat. Thymic carcinoma rarely occurs in children. We reported a case of undifferentiated thymic carcinoma in 11 months old female. After two courses of chemotherapy the patient developed increasing respiratory compression and unfortunately died because of respiratory failure.

Keywords:

Anterior Mediastinal Mass, Rare Pediatric Tumors, Thymic Carcinoma

Downloads

Download data is not yet available.

References

D. A. Chung, “Thymic Carcinoma - Analysis of Nineteen Clinicopathological Studies,” Thorac. Cardiovasc. Surg., vol. 48, no. 2, pp. 114–119, Apr. 2000.

S. R. y Cajal and S. Suster, “Primary Thymic Epithelial Neoplasms in Children,” Am. J. Surg. Pathol., vol. 15, no. 5, pp. 466–474, 1991.

J. L. Grosfeld, M. A. Skinner, F. J. Rescorla, K. W. West, and L. R. Scherer, “Mediastinal tumors in children: Experience with 196 cases,” Ann. Surg. Oncol., vol. 1, no. 2, pp. 121–127, Mar. 1994.

J. Rosai and L. H. Sobin, Histological Typing of Tumours of the Thymus. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999.

M. Marino and H. K. Müller-Hermelink, “Thymoma and thymic carcinoma. Relation of thymoma epithelial cells to the cortical and medullary differentiation of thymus.,” Virchows Arch. A. Pathol. Anat. Histopathol., vol. 407, no. 2, pp. 119–49, 1985.

C.-A. Hartmann, C. Roth, C. Minck, and G. Niedobitek, “Thymic carcinoma,” J. Cancer Res. Clin. Oncol., vol. 116, no. 1, pp. 69–82, Jan. 1990.

M. R. Wick, B. W. Scheithauer, L. H. Weiland, and P. E. Bernatz, “Primary thymic carcinomas.,” Am. J. Surg. Pathol., vol. 6, no. 7, pp. 613–30, Oct. 1982.

K. Swinborne-Sheldrake, G. F. Gray, and A. D. Glick, “Thymic epithelial neoplasms.,” South. Med. J., vol. 78, no. 7, pp. 790–800, Jul. 1985.

A. Masaoka, Y. Monden, K. Nakahara, and T. Tanioka, “Follow-up study of thymomas with special reference to their clinical stages,” Cancer, vol. 48, no. 11, pp. 2485–2492, Dec. 1981.

S. Suster and J. Rosai, “Thymic carcinoma. A clinicopathologic study of 60 cases.,” Cancer, vol. 67, no. 4, pp. 1025–32, Feb. 1991.

L. Chalabreysse, B. Etienne-Mastroianni, P. Adeleine, J.-F. Cordier, T. Greenland, and F. Thivolet-Bejui, “Thymic carcinoma: a clinicopathological and immunohistological study of 19 cases,” Histopathology, vol. 44, no. 4, pp. 367–374, Apr. 2004.

C. P. Hsu et al., “Thymic carcinoma. Ten years’ experience in twenty patients.,” J. Thorac. Cardiovasc. Surg., vol. 107, no. 2, pp. 615–20, Feb. 1994.

K. Kondo and Y. Monden, “Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan,” Ann. Thorac. Surg., vol. 76, no. 3, pp. 878–884, Sep. 2003.

A. Ríos et al., “Prognostic factors in thymic epithelial neoplasms,” Eur. J. Cardio-Thoracic Surg., vol. 21, no. 2, pp. 307–313, Feb. 2002.