International Annals of Science https://journals.aijr.org/index.php/ias <p align="justify"><a title="Click for Journal homepage" href="https://doi.org/10.21467/ias" target="_blank" rel="noopener"><img style="float: right; padding-left: 15px; padding-right: 5px;" src="/public/site/images/aabahishti/IAS_cover_page.jpg" alt="IAS"></a> International Annals of science is an open access, peer-reviewed, online multidisciplinary journal dedicated to publishing high-quality research in all areas of the Computer, Mathematics, Physical, Chemical, Biological, and Earth Sciences. Papers published by the journal represent important advances of significance within each field by AIJR Publisher.<br>International Annals of Science is registered with CrossRef with doi:10.21467/ias and ISSN of this journal is &nbsp;2456-7132 [online].</p> AIJR Publisher en-US International Annals of Science 2456-7132 <div id="copyrightNotice"> <p>Author(s) retains full copyright of their article and grants non-exclusive publishing right to International Annals of Science and its publisher "<a title="AIJR Publisher homepage" href="https://aijr.org/" target="_blank" rel="noopener">AIJR</a> (India)". Author(s) can archive pre-print, post-print, and published version/PDF to any open access, institutional repository, social media, or personal website provided that Published source must be acknowledged with citation and link to publisher version.<br />Click <a title="Copyright Policy" href="https://aijr.org/about/policies/copyright/" target="_blank" rel="noopener">here</a> for more information on Copyright policy<br />Click <a title="Licensing Policy" href="https://journals.aijr.org/index.php/ias/about#licensing">here</a> for more information on Licensing policy</p> </div> Critical COVID-19 Pneumonia with Acute Respiratory Failure in a Healthy 12-year-old Girl https://journals.aijr.org/index.php/ias/article/view/4056 <p>The authors present a case report of an otherwise healthy, fully immunized 12-year-old girl who had a critical course of COVID-19 infection with acute respiratory failure. The epidemiologic history was positive for COVID-19, and she tested PCR positive resulting from a nasopharyngeal swab. She was presented with fever and cough to a regional pediatric department, and she was immediately intubated and transferred to a pediatric ICU in a University Hospital. CT of the thorax revealed bilateral consolidation with the tree-in-bud signs. Her condition required artificial ventilation support for 13 days. Remdesivir, pronation, high dose Ascorbic acid with Thiamine, and combined antimicrobial therapy were successfully used. The patient made a full clinical recovery. This case report is unique because of a very scarce critical course of COVID-19 infection in children. It demonstrates the successful use of a combined therapeutic approach with artificial ventilation, pronation, Remdesivir, and combined antimicrobial therapy. Clinical symptoms, laboratory results, imaging methods, and therapeutic attitude are mentioned to share our experience with the medical community.</p> Karolina Dolezalova Cabelova Tamara Tomas Hecht Pavel Heinige Copyright (c) 2021 Karolina Dolezalova, Cabelova Tamara, Tomas Hecht, Pavel Heinige http://creativecommons.org/licenses/by-nc/4.0 2021-09-07 2021-09-07 11 1 3 9 10.21467/ias.11.1.3-9