Therapeutic Application of Honey Against Ige-Mediated Type 1 Hypersensitivity Reactions: A Systematic Review

Daphne Michaella D Quitain; Ma. Jenina B Balasolla; Danielle Krisha S Barber; Rencel Shane J Cainglet; Junnela F Colorico; Allyna Kristel R Escantilla; Aira Palomeno; Kristine Claire M Quiambao; Luis Dominick B Antig

doi:10.21467/ajgr.14.1.51-60

Authors

Daphne Michaella D Quitain Department of Medical Technology, Far Eastern University https://orcid.org/0009-0002-5274-0636
Ma. Jenina B Balasolla Department of Medical Technology, Far Eastern University https://orcid.org/0009-0004-3385-2020
Danielle Krisha S Barber Department of Medical Technology, Far Eastern University
Rencel Shane J Cainglet Department of Medical Technology, Far Eastern University
Junnela F Colorico Department of Medical Technology, Far Eastern University
Allyna Kristel R Escantilla Department of Medical Technology, Far Eastern University
Aira Palomeno Department of Medical Technology, Far Eastern University
Kristine Claire M Quiambao Department of Medical Technology, Far Eastern University
Luis Dominick B Antig Department of Medical Technology, Far Eastern University

DOI:

https://doi.org/10.21467/ajgr.14.1.51-60

Abstract

In contemporary times, the use of traditional remedies is still evident. One of the primary items foremost emphasized today is honey. Aside from its natural sweetener capacity, modern science highlights its potential therapeutic capabilities, including anti-inflammatory and immunoregulatory properties in different Type I Hypersensitivity conditions. This systematic review analyzed nine credible experimental studies to objectify different types of honey and its application and effect in different Type I Hypersensitivity clinical manifestations. The abundance of evidence granting IgE mediated disorders which includes Allergic Asthma, Vernal Keratoconjunctivitis, Allergic Fungal Rhinosinusitis, Allergic Rhinitis, and Atopic Dermatitis in both preclinical and clinical analysis revealed honey to be a contributing factor in suppressing different clinical manifestations of the associated conditions. The systematic review can evaluate and categorize the potential therapeutic capabilities of honey in different IgE-mediated Type I Hypersensitivity Reactions, thus, enabling a comprehended integration towards assisting the application within the clinical setting.

Keywords:

Honey, Type I Hypersensitivity Reactions, Chrysin

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