Green Peptide–nanomaterials; A Friendly Healing Touch for Skin Wound Regeneration

Debjani Nath; Pratyusha Banerjee; Anugrah Ray; Baishakhi Bairagi

doi:10.21467/anr.2.1.14-31

Authors

Debjani Nath Department of Zoology, University of Kalyani
Pratyusha Banerjee Department of Zoology, University of Kalyani
Anugrah Ray Department of Zoology, University of Kalyani
Baishakhi Bairagi Department of Zoology, University of Kalyani

DOI:

https://doi.org/10.21467/anr.2.1.14-31

Abstract

The complex phenomenon by which the body responds to any injury of skin or tissue is known as wound healing. A number of phases like exudative, proliferative, and extracellular matrix remodeling are orchestrated events to be occurred involving blood cells, parenchymal cells, and different soluble mediators. Different internal, as well as external factors, regulate the speed and quality of healing. The delay in wound healing process causes the chronic wound or scar formation. At the present moment, the upscale research for identification of agents causing accelerated healing is important. Moreover, the biocompatibility of the accelerators needs to be investigated. Recent biomedical researches for wound care target to provide antimicrobial protection as well as matrix scaffolding for quick repairing of the skin tissue. In recent studies with natural peptides have shown that they are important components in developing the nano-medicines for their usefulness and therapeutic efficiency. New therapeutic formulations can be developed using these natural peptides utilizing different nanoparticle delivery system. This review deals with the developmental study on efficient wound care system where the possible use of natural peptides in combination with nanomaterials has been explored. A trial has also been made on the findings made over the past few years on the use of peptides as tissue regenerating agents through effective wound healing pathway.

Keywords:

wound healing, tissue regeneration, nanomaterial, green peptide nanoparticles, biocompatibility, bioactive

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